NQO1 regulates mitotic progression and response to mitotic stress through modulating SIRT2 activity
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چکیده
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NudC Deacetylation Regulates Mitotic Progression
Mitosis is largely driven by posttranslational modifications of proteins. Recent studies suggest that protein acetylation is prevalent in mitosis, but how protein acetylation/deacetylation regulates mitotic progression remains unclear. Nuclear distribution protein C (NudC), a conserved protein that regulates cell division, was previously shown to be acetylated. We found that NudC acetylation wa...
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ژورنال
عنوان ژورنال: Free Radical Biology and Medicine
سال: 2018
ISSN: 0891-5849
DOI: 10.1016/j.freeradbiomed.2018.08.009